Pulmonary Hypertension Treatment for Newborns in Coimbatore

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pphn treatment in Coimbatore

What is Persistent Pulmonary Hypertension in newborns(PPHN)?

PPHN is a significant breathing issue that affects babies. It most commonly affects full-term newborns or babies born at 34 weeks or more. Other forms of breathing problems are common in these babies.

Persistent hypertension of the newborn and persistent fetal circulation syndrome are other names for this illness.

How does PPHN affect the newborn?

The blood vessels in the lungs should open up and start circulating blood into the lungs as soon as the infant is born and takes their first breath. This allows the baby's brain and the rest of the body to receive oxygen.

  • The blood arteries in the baby's lungs do not fully open when a baby has PPHN.
  • A lack of blood flow to the lungs is a result of restricted blood vessels.
  • This means that the brain and the rest of the body may be deficient in oxygen.
  • There is high-pressure build-up in the lungs' blood veins (pulmonary hypertension).
  • The baby's heart and lungs could be damaged by the high pressure.

What are the warning signs in a newborn with persistent pulmonary hypertension?

At birth or within the first few hours following birth, the newborn will have breathing difficulty and display indicators of low oxygen.

  • Breathing and heart rate are both relatively fast.
  • When the baby is breathing, you'll hear grunting or moaning.
  • Retractions (the skin between and under the ribs pulls in during fast and hard breathing)
  • Blue lips or lips around the mouth, as well as blue hands and feet (cyanosis)
  • Even after receiving oxygen, blood oxygen levels are low and oxygen saturation levels are low.
  • Blood pressure that is too low
  • Cyanosis is a condition in which a baby's skin has a bluish colour despite obtaining additional oxygen.
  • As a result, a baby with a heart murmur has an additional or abnormal heart sound.

Risk factors associated with Persistent Hypertension in the Newborn

Although the cause is unknown, many variables raise the incidence of PPHN neonates. These elements include:

  1. Aspiration of meconium
  2. Infection
  3. Respiratory distress syndrome (RDS) is a condition that affects the lungs. This breathing issue affects infants whose lungs have not fully grown.
  4. Lack of oxygen before or during birth.
  5. Diaphragmatic hernia: A diaphragmatic hernia is a hole in the diaphragm, the muscle that separates the chest from the belly. Organs from one side push through the hole, causing a hernia; in this example, organs from the abdomen intrude on the chest.
pulmonary hypertension specialists in Coimbatore

Diagnosis of the PPHN condition:

Various imaging and laboratory tests can assess pulmonary pressure in a newborn. These may include the following:

Treatment options for Persistent Pulmonary Hypertension

PPHN treatment aims to raise blood oxygen levels, open pulmonary blood veins, and maintain normal blood pressure.

Nasal cannula:

A nasal cannula is a medical device that allows PPHN newborns with low oxygen levels to receive supplementary oxygen therapy. Nasal cannulas are divided into two categories: low flow and high flow.

Continuous Positive Air Pressure (CPAP):

This equipment softly pushes the air or oxygen into the lungs.


This gadget will breathe for your baby until they can breathe independently. The infant's windpipe is inserted with a breathing tube. This is referred to as intubation (in too BAY shun). The ventilator is then connected to the breathing tube. The ventilator is designed to provide the newborn with consistent and even breathing.

High-frequency oscillation ventilation:

This is a unique form of a ventilation system. Through a breathing tube, it may give quick, brief bursts of air.

Inhaled Nitric oxide:

A life changer for babies with PPHN. Nitiric oxide is a special gas with its delivery system, which when provided to a baby with PPHN increases oxygen levels drastically and decreases the need for ECMO. Inhaled nitric oxide has revolutionized the treatment for PPHN.

Extracorporeal Membrane Oxygenation (ECMO):

For infants with severe heart or lung failure, an extracorporeal membrane oxygenation (ECMO) system can be used. While the PPHN resolves, the ECMO provides temporary support by supplying oxygen to the brain and body.

An external pump and oxygenator are used to take over the heart and lungs of your baby in ECMO, which is similar to a heart-lung bypass system. Therefore, treatment for PPHN newborns in Coimbatore can provide you with complete treatment of the condition in newborns without any complications.

Targets of Persistent Pulmonary Hypertension

The goal of PPHN treatment is to

Keep systemic blood pressure stable

Reduce pulmonary vascular resistance

supply tissues with the oxygen they need

minimize lesions caused by excessive levels of inspired oxygen

Questions? Answered!

Pulmonary hypertension in premature infants is commonly outgrown as they begin to feed and develop. However, many babies do well with oxygen, medicine, and regular follow-up care after they leave the NICU.

PPHN affects about one in every 1,250 infants. It occurs most frequently in full-term infants or infants born after their due dates. In addition, it frequently happens after a difficult delivery. Your child's doctor may run tests to see if they have this condition.

Echocardiography is used to confirm that the person has PPHN. Among the most important findings are an abnormally large right ventricle, a leftward deviation of the interventricular septum, a tricuspid regurgitation, and right-to-left shunting at the levels of the patent foramen ovale and the patent ductus arteriosus.

Persistent pulmonary hypertension of the newborn (PPHN) is a very dangerous condition that can make a baby not get enough oxygen after it is born. It can also make the baby sick. As the baby grows inside the mother, the placenta gives them all of the oxygen they need through this tube. As a result, most of the baby's blood goes over its lungs.

The most commonly used treatments for PPHN neonates include: when a baby is sick, they use a special ventilator that breathes for them at a very fast rate to help with blood pressure, such as giving medicine intravenously (IV or through the vein), extracorporeal membrane oxygenation (ECMO) is used as a last-ditch treatment. This is when the heart and lungs are temporarily bypassed.

The cost of PPHN treatment in Coimbatore relies on the surgeon's fee, and other miscellaneous expenses. Along though accurate diagnosis may help you get an idea of the overall cost.

A combination of approaches like lifestyle modifications, medications, and medical procedures is needed to reduce pulmonary hypertension. Lifestyle changes including maintaining a healthy weight, consistent exercising, and avoiding smoking will help in managing symptoms.

Stress is not the sole reason for pulmonary hypertension, but it has the potential to trigger the existing conditions and contribute to overall cardiovascular strain. Persistent stress may result in hypertension and heart disease, which will trigger the risk factors for developing pulmonary hypertension.

Pulmonary hypertension is widely seen among the age group of 30 to 60 years. Also, getting older will increase the chances of developing group 1 pulmonary hypertension, known as pulmonary arterial hypertension (PAH). PAH from an unexplained cause is more common in adults.

What Our Patients Are Saying

Our Department’s Experience

Our Department of Neonatology has treated over 20,000+ pulmonary pressure in newborns over the last 49 years. Our highly experienced Neonatologists will ensure your precious child receives the best PPHN treatment in Coimbatore.

Why Choose Sri Ramakrishna Hospital?

Over 49+ Years of Medical Service

Highly Experienced Neonatologists

Best in Class Medical Infrastructure

Latest and Safest Treatment Methods

Our Doctors and their Experience

Our highly experienced Neonatologists have immense experience in providing the best pulmonary hypertension treatment in Coimbatore.

Dr. Siddartha Buddhavarapu is a Consultant Neonatologist of the Department of Neonatology at Sri Ramakrishna Hospital. He has over 14 years of experience and is an expert in treating extreme preterm babies, (as small as 24 weeks) complete surgical & Cardiac conditions.

MD (Paed), Fellowship in Neonatal Perinatal Medicine University of Calgary,
Canada Consultant Neonatologist & HOD

Dr. Suja Mariam is a Consultant Neonatologist of the Department of Neonatology at Sri Ramakrishna Hospital. She has over 11 years of experience and has an expertise in managing extreme preterm neonates upto 23 weeks of gestation.

MD (Paed), DM (Neonatology)
Consultant Neonatologist

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Sri Ramakrishna Hospital

  • Treated 10,00,000+ Patients while Counting on state of the art infrastructure and medical equipment.
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395, Sarojini Naidu Rd, New Siddhapudur, Coimbatore, Tamil Nadu 641044.

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