Medical Oncology

Chemotherapy is the use of anti-cancer (cytotoxic) drugs to destroy cancer cells.
Various roles of chemotherapy are

  • Primary Treatment
  • Neo adjuvant Treatment
  • Adjuvant Treatment
  • Regional Treatment
  • Induction Treatment
  • Palliation

Combination Chemotherapy is better because

  • It provides maximal cell kill with minimal toxicity
  • It provides a broader range of interaction between drugs & tumour cells in heteogenous tumour population
  • It may slow the subsequent development of drug resistance
Chemotherapeutically curable cancers include
  • Chorio carcinoma
  • Acute promyelocytic leukemia
  • Burkitt’s lymphoma
  • Hodgkin’s disease
  • Large follicular centre cell lymphoma
  • Testicular carcinoma
  • Acute lymphocytic leukemia of childhood
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